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This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
1500038E17Rik; AEY11; ALL3; AN; AN2; Aniridia type II protein; B-cell lineage specific activator; B-cell-specific transcription factor; BSAP; CDHS; D11S812E; Dey; Dickie's small eye; EBB-1; EMBL:BAE79272.1}; FSGS7; FVH1; Gsfaey11; hbs; homeodomain protein PAX3; hunchback; HUP1; HUP2; HUP48; KLP; KPD; MGDA; MODY9; Oculorhombin; OFC2; Opdc; optic disc coloboma; paired box 1; paired box 2; paired box 3; paired box 4; paired box 5; paired box 6; paired box 7; paired box 8; paired box 9; paired box gene 1; paired box gene 2; paired box gene 3; paired box gene 4; paired box gene 5; paired box gene 6; paired box gene 7; paired box gene 8; paired box gene 9; Paired box homeotic gene 1; paired box homeotic gene 2; paired box homeotic gene 3; paired box homeotic gene 5; paired box homeotic gene 6; paired box homeotic gene 7; paired box homeotic gene-6; paired box protein Pax-1; Paired box protein Pax-2; paired box protein Pax-3; Paired box protein Pax-4; paired box protein Pax-5; Paired box protein Pax-6; paired box protein Pax-7; Paired box protein Pax-8; paired box protein Pax-9; paired box transcription factor PAX7; paired domain gene 3; paired domain gene 4; paired domain gene 5; paired domain gene 7; paired domain gene 8; paired domain gene 9; paired domain gene HuP2; paired domain gene HuP48; PAPRS; PAX1; Pax-1; PAX2; Pax-2; PAX3; Pax-3; PAX3/FKHR fusion; PAX4; Pax-4; PAX5; Pax-5; Pax5 variant 1; Pax5 variant 2; PAX6; Pax-6; Pax7; Pax-7; PAX7 transcriptional factor; PAX7B; PAX8; Pax-8; Pax-8 protein; Pax9; Pax-9; pax9 {ECO:0000312; RGD1564360; RGD1565236; RMS2; Sey; small eye; Sp; splotch; STHAG3; transcription factor PAX 5; un; undulated; WAGR; wavy tail; WS1; WS3; wt
150 µL
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